Hi
It might be your Triggers link on the main screen has become inoperative? See attached screenshot, this happened to me this morning. I have a feeling it's a Windows Update that has caused it. I tried all the usual re-allowing though firewall etc. Opening a new Profile seems to have corrected it.
UPDATE:
May be unrelated to your problem, if you have multiple monitors, and if you restart the program with one of the screens switched off, the trigger window etc. might be on the screen which is switched off! Fixed by switching on the other monitor and dragging the window back to the main screen.